Integrilin Dosing Chart

35H49N11O9S2 and a molecular weight of 83196. In patients with creatinine clearance CrCl 60 mLmin give 25 mcgkg bolus within 5 minutes followed by an infusion of 0075 mcgkgmin for up to 18 hours.

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Differences Between Eptifibatide And Abciximab The Two Most Commonly Download Table

Aspirin 160 to 325 mg should be given 1 to 24 hours prior to PCI and daily thereafter.

Integrilin dosing chart. INTEGRILIN Dosing Charts by Weight. Eptifibatide Injection Dosing Charts by Weight Patient Weight 180-mcgkg Bolus Volume 2-mcgkgmin Infusion Volume CrCl greater than or equal to 50 mLmin 1-mcgkgmin Infusion Volume CrCl less than 50 mLmin kg lb from 2 mgmL vial from 2-mgmL 100-mL GALAXY container from 075-mgmL 100-mL GALAXY container from 2-mgmL 100-mL GALAXY. The infusion may also contain up to 40mEqL of potassium chloride.

Dosing Instructions Following PCI. Target aPTT 50 -. Refer to prescribing information for bolus volume and infusion rate to be administered based on patient.

180 µgkg IV bolus administered immediately before the initiation of PCI followed by a continuous infusion of 20 µgkgmin and a second 180 µgkg bolus 10 minutes after the first bolus. Eptifibatide injection is a clear colorless sterile non-pyrogenic solution for intravenous IV use with an empirical formula of C 35 H 49 N 11 O 9 S 2 and a molecular weight of 83196. The bolus dose of Integrilin eptifibatide should be withdrawn from the 10-ml vial into a syringe and administered IV push over 1-2 minutes.

Usual Dosing Adults Percutaneous Coronary Intervention PCI. Each 10-mL vial contains 2 mgmL of eptifibatide and each 100-mL vial contains either 075 mgmL of eptifibatide or 2 mgmL of eptifibatide. INTEGRILINDosing Charts by Weight Patient Weight 180-mcgkg Bolus Volume 2-mcgkgmin Infusion Volume CrCl greater than or equal to 50mLmin 1-mcgkgmin Infusion Volume CrCl less than 50mLmin kg lb from 2-mgmL vial from 2-mgmL 100-mL vial from 075-mgmL 100-mL vial from 2-mgmL 100-mL vial from 075-mgmL 100-mL vial.

In patients with moderate renal impairment creatinine clearance 30 - 50 mlmin an intravenous bolus of 180 microgramkg should be administered followed by a continuous infusion dose of 10 microgramkgmin for the duration of therapy. Patient Weight 180-mcgkg Bolus Volume 2-mcgkgmin Infusion Volume CrCl greater than or equal to 50 mLmin 1-mcgkgmin Infusion Volume CrCl less than 50 mLmin kg lb from 2-mgmL vial from 2-mgmL 100-mL vial from 075-mgmL 100-mL vial from 2-mgmL 100-mL vial from 075-mgmL 100-mL vial 37-41. 226 mg for patients weighing 121 kg.

Administer intravenously 25 mcgkg within 5 minutes and then 015 mcgkgmin for up to 18 hours. If Calculated CrCl 50 mlmin follow bolus with continuous infusion at. Administer concomitantly with heparin dosed to achieve the following parameters.

Administer 60-unitskg bolus initially in patients not treated with heparin within 6 hours prior to PCI. Dosing and Administration High-Dose Bolus Regimen. Bolus with 180 mcgkg over 1-2 minutes.

Each 10-mL vial contains 2 mgmL of eptifibatide and each 100-mL vial contains 075 mgmL of eptifibatide. 15 mghour for patients weighing 121 kg. Percutaneous coronary interventions PCI.

INTEGRILIN Dosing Charts by Weight. INTEGRILIN Dosing Charts by Weight. Continue infusion for 12-24 hours post PCI.

Administer undiluted from vial. The infusion of 175 mgkgh may be continued for up to 4 h post-PCI and at a reduced dose of 025 mgkgh for an additional 412 h as clinically necessary. Integrilin eptifibatide Injection is a clear colorless sterile non-pyrogenic solution for.

Patient Weight 180 µgkg Bolus Volume 20 µgkgmin Infusion Volume 10 µgkgmin Infusion Volume kg lb from 2 mgmL vial from 2 mgmL 100-mL vial from 075 mgmL 100-mL vial from 2 mgmL 100-mL vial from 075 mgmL 100-mL vial 3741. Intravenous IV use with an empirical formula of C. If Calculated CrCl 50 mlmin follow bolus with continuous infusion at 2 mcgkgmin for at least 18-24 hours after intervention.

2 mcgkgmin continuous IV infusion max. In STEMI patients the infusion of 175 mgkgh should be continued for up to 4. 75 mg100 ml vials 075 mgmL infuse at 2 mcgkgmin.

Patient Weight 180-mcgkgBolus Volume 2-mcgkgminInfusion VolumeCrCl greater than or equal to 50 mLmin 1-mcgkgminInfusion VolumeCrCl less than 50 mLmin kg lb from 2-mgmL vial from 2-mgmL 100-mL vial from 075-mgmL 100-mL vial from 2-mgmL 100-mL vial from 075-mgmL 100-mL vial 37-41. Integrilin should be given concomitantly with heparin to achieve a target ACT of 200 to 300 seconds. This recommendation is based on pharmacodynamic and pharmacokinetic data.

Integrilin eptifibatide may be administered in the same IV line with 09 NaCl or 09 NaCl 5 dextrose. 180 mcgkg IV bolus max. Unstable anginanon-ST elevation myocardial infarction.